Lost Signs

When the Defenders battled the Zodiac, not all twelve signs were there. Leading the cadre was Scorpio, brother of S.H.I.E.L.D. agent Nick Fury. The rest of the Zodiac were Life Model Decoys that Scorpio designed using S.H.I.E.L.D. technology. But activating these androids prematurely caused three of them to malfunction: Capricorn, Pisces and Virgo. I am uncertain of the astrological implications of losing these particular signs, but Scorpio had designated Virgo—the only female in the group—as his love interest. The heartbroken criminal killed himself (Defenders #50).

Two of the androids, Sagittarius and Libra, would return to lead other supervillains pretending to be Defenders for a Day.

This image of Scorpio (Jake Fury) comes from Defenders #50.